Deprescribing diabetes medications for older adults living with frailty

IC Lega, W Thompson, LM McCarthy - CMAJ, 2024 - Can Med Assoc
Treating to intensive glycemic targets (glycosylated hemoglobin [A 1c]< 7%) increases the
risk of adverse events and is unlikely to provide benefit given the reduced life expectancy of …

[HTML][HTML] Diabetes and frail older patients: Glycemic control and prescription profile in real life

AS Mangé, A Pagès, S Sourdet, P Cestac… - Pharmacy, 2021 - mdpi.com
(1) Background: The latest recommendations for diabetes management adapt the objectives
of glycemic control to the frailty profile in older patients. The purpose of this study was to …

The risks and benefits of implementing glycemic control guidelines in frail older adults with diabetes mellitus

SJ Lee, WJ Boscardin, I Stijacic Cenzer… - Journal of the …, 2011 - Wiley Online Library
OBJECTIVES: To determine the hypo‐and hyperglycemic outcomes associated with
implementing the American Geriatrics Society (AGS) guideline for a glycosylated …

[HTML][HTML] Diabetes and frailty: an expert consensus statement on the management of older adults with type 2 diabetes

WD Strain, S Down, P Brown, A Puttanna, A Sinclair - Diabetes Therapy, 2021 - Springer
Prognosis and appropriate treatment goals for older adults with diabetes vary greatly
according to frailty. It is now recognised that changes may be needed to diabetes …

Diabetes in the frail elderly: individualization of glycemic management

T Laubscher, L Regier, J Bareham - Canadian Family Physician, 2012 - cfp.ca
Older adults with diabetes who are otherwise healthy and who have considerable life
expectancy (more than 10 years) should generally receive diabetes care with goals and …

Evidence-informed guidelines for treating frail older adults with type 2 diabetes: from the Diabetes Care Program of Nova Scotia (DCPNS) and the Palliative and …

LH Mallery, T Ransom, B Steeves, B Cook… - Journal of the American …, 2013 - Elsevier
Clinical practice guidelines specific to the medical care of frail older adults have yet to be
widely disseminated. Because of the complex conditions associated with frailty, guidelines …

Care of elderly patients with diabetes mellitus: a focus on frailty

LK Chen, YM Chen, MH Lin, LN Peng… - Ageing research reviews, 2010 - Elsevier
The prevalence and incidence of type 2 diabetes mellitus (DM) increase with age, and its
diagnosis and treatment in older people present a challenge. Applying evidence to elderly …

Management of type 2 diabetes in patients with frailty

K Hawker, R Akter, F Molnar, C Frank - Canadian Family Physician, 2024 - cfp.ca
Diabetes management should be individualized. 1 Newer antihyperglycemic agents (Table
1) such as glucagonlike peptide-1 receptor agonists (GLP1-RAs), dipeptidyl peptidase 4 …

Evaluating glucose‐lowering treatment in older people with diabetes: lessons from the IMPERIUM trial

AJ Sinclair, SR Heller, RE Pratley… - Diabetes, Obesity …, 2020 - Wiley Online Library
Understanding the benefits and risks of treatments to be used by older individuals (≥ 65
years old) is critical for informed therapeutic decisions. Glucose‐lowering therapy for older …

[HTML][HTML] A modern approach to glucose-lowering therapy in frail older people with type 2 diabetes mellitus

AH Abdelhafiz, D Pennells… - Expert Review of …, 2022 - Taylor & Francis
With increasing age, frailty is recognized as an emerging new diabetes-related complication
[1]. As life expectancy is increasing, the number of older people with comorbid diabetes and …