Conspectus The implementation of any chemical reaction in a structurally complex setting (
King , SM J. Org. Chem. 2014 , 79 , 8937 ) confronts structurally defined barriers: steric …

A combination of cobalt and nickel catalytic cycles enables a highly branch-selective (Markovnikov)
olefin hydroarylation. Radical cyclization and ring scission experiments are …

The synthesis of highly functionalized pyrroles has been achieved by reaction of rhodium-
stabilized imino-carbenes with furans. The reaction features an initial [3+ 2] annulation to …

Metal-hydride hydrogen atom transfer (MHAT) has emerged as a useful tool to form
quaternary carbons from alkenes via hydrofunctionalization. Methods to date that cross-couple …

Alkene hydroarylation forms carbon–carbon bonds between two foundational building
blocks of organic chemistry: olefins and aromatic rings. In the absence of electronic bias or …

Metal-hydride hydrogen atom transfer (MHAT) functionalizes alkenes with predictable branched
(Markovnikov) selectivity. The breadth of these transformations has been confined to π-…

Reproductive medical tourism is by some accounts a multibillion dollar industry globally.
The seeking by clients in high income nations of surrogate mothers in low income nations, …

We systematically reviewed randomized controlled trials of interventions to improve the
health of people during imprisonment or in the year after release. We searched 14 biomedical …

DNA Encoded Libraries have proven immensely powerful tools for lead identification. The
ability to screen billions of compounds at once has spurred increasing interest in DEL …

Background Many people experience imprisonment each year, and this population bears a
disproportionate burden of morbidity and mortality. States have an obligation to provide …