RT Journal Article
SR Electronic
T1 Severe necrotizing pancreatitis following combined hepatitis A and B vaccination
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 339
OP 342
DO 10.1503/cmaj.060360
VO 176
IS 3
A1 Shlomovitz, Eran
A1 Davies, Ward
A1 Cairns, Ewa
A1 Brintnell, William C.
A1 Goldszmidt, Mark
A1 Dresser, George K.
YR 2007
UL http://www.cmaj.ca/content/176/3/339.abstract
AB Necrotizing pancreatitis is a severe form of pancreatitis and is associated with substantial morbidity and mortality. We report a case of necrotizing pancreatitis that developed following combined hepatitis A and B vaccination. No other causes of pancreatitis could be determined. Although confirming the diagnosis is challenging, 3 main factors suggest a possible link to the vaccine: the chronology of the events, the patient's human leukocyte antigen genotype and the incongruent immune response to the vaccine components. This report serves to alert physicians to the possible development of necrotizing pancreatitis after vaccination.