Table 2:

Benefits of treatment for obstructive sleep apnea, by disease severity

Severity of OSAImpact of treatment
CPAPOAMMA
Mild (7)AHI: Decreases AHI
Symptoms:
Unclear impact on ESS
Unclear impact on QoL
Cardiovascular:
Unclear effect on BP
Unclear reduction in CV events
Cerebrovascular:
Unclear impact
AHI: Decreases AHI
Symptoms:
Unclear impact on ESS
Unclear impact on QoL
Cardiovascular:
Unclear impact on BP
Unclear impact on CV events
Cerebrovascular:
Unclear impact
AHI: Unclear impact
Symptoms:
Unclear impact
Cardiovascular:
Unclear impact on CV events
Cerebrovascular:
Unclear impact
Moderate to severe (4)AHI: Decreases AHI
Symptoms:
Reduces ESS
Improves QoL (5), (6)
Cardiovascular:
Decreases BP
Improves responsiveness of atrial fibrillation to treatment
Unclear impact on CV events
Cerebrovascular:
May decrease risk of stroke
May improve outcomes after stroke
AHI: Decreases AHI
Symptoms:
Reduces ESS
Unclear impact on QoL
Cardiovascular:
Decreases BP
Unclear impact on CV events
Cerebrovascular:
Unclear impact
AHI: Decreases AHI
Symptoms:
Reduces ESS
Unclear impact on QoL
Cardiovascular:
Decreases BP
Unclear impact on CV events
Cerebrovascular:
Unclear impact
  • Note: AHI = apnea–hypopnea index, BP = blood pressure, CPAP = continuous positive airway pressure, CV = cardiovascular, ESS = Epworth Sleepiness Scale, MMA = maxillomandibular advancement, OA = oral appliance, OSA = obstructive sleep apnea, QoL = quality of life.