Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions
ContextA number of countries have implemented a policy of universal leukoreduction of their
blood supply, but the potential role of leukoreduction in decreasing postoperative mortality …
blood supply, but the potential role of leukoreduction in decreasing postoperative mortality …
A randomized controlled trial comparing the frequency of acute reactions to plasma‐removed platelets and prestorage WBC‐reduced platelets
…, RM Meyer, JH Lipton, IR Walker, GD Sher… - …, 2002 - Wiley Online Library
BACKGROUND: Removal of the plasma supernatant from platelets before transfusion is
effective in preventing acute reactions to platelets caused by cytokines. Prestorage WBC …
effective in preventing acute reactions to platelets caused by cytokines. Prestorage WBC …
Incidence and estimated rates of residual risk for HIV, hepatitis C, hepatitis B and human T-cell lymphotropic viruses in blood donors in Canada, 1990–2000
…, P Driezen, S Deeks, DE Hone, SF O'Brien, G Sher - Cmaj, 2003 - Can Med Assoc
Background: Since 1990, the Canadian Red Cross Society and Canadian Blood Services
have been testing blood donors for hepatitis C virus (HCV) antibody and HCV nucleic acids …
have been testing blood donors for hepatitis C virus (HCV) antibody and HCV nucleic acids …
A multivariable model for predicting the need for blood transfusion in patients undergoing first‐time elective coronary bypass graft surgery
K Karkouti, MM Cohen, SA McCluskey, GD Sher - Transfusion, 2001 - Wiley Online Library
BACKGROUND: The incidence of blood transfusion in coronary artery bypass graft (CABG)
surgery remains high. Preoperative identification of those at high risk for requiring blood will …
surgery remains high. Preoperative identification of those at high risk for requiring blood will …
[HTML][HTML] Extended therapy with intravenous arginine butyrate in patients with β-hemoglobinopathies
GD Sher, GD Ginder, J Little, S Yang… - … England Journal of …, 1995 - Mass Medical Soc
Background Enhanced production of fetal hemoglobin lessens the severity of β-thalassemia
and sickle cell disease. Intravenous infusion of arginine butyrate can increase the number of …
and sickle cell disease. Intravenous infusion of arginine butyrate can increase the number of …
Allogeneic red blood cell transfusion is an independent risk factor for the development of postoperative bacterial infection
…, WH Geerts, C Greenwood, RS McLeod, GD Sher - Vox sanguinis, 2000 - karger.com
Background and Objectives: Allogeneic red blood cell transfusions may exert immunomodulatory
effects in recipients including an increased rate of postoperative bacterial infection. It is …
effects in recipients including an increased rate of postoperative bacterial infection. It is …
Transfusion-transmitted malaria in Canada
…, A Giulivi, M Bodie-Collins, F Hindieh, RS John, G Sher… - Cmaj, 2001 - Can Med Assoc
THREE CASES OF TRANSFUSION-TRANSMITTED MALARIA in Canada are described.
Although very rare, this diagnosis should be considered in transfusion recipients who have …
Although very rare, this diagnosis should be considered in transfusion recipients who have …
Diabetic nephropathy in hypertransfused patients with β-thalassemia: the role of oxidative stress
…, DC Lehotay, X Luo, W Bartfay, B Tyler, GD Sher - Diabetes …, 1998 - Am Diabetes Assoc
OBJECTIVE Pathogenesis of diabetes-related microvascular complications involving
oxidative damage by free radicals has been demonstrated. Free radical generation has been …
oxidative damage by free radicals has been demonstrated. Free radical generation has been …
Proceedings of a consensus conference: prevention of post-transfusion CMV in the era of universal leukoreduction
…, M Goldman, JJ Freedman, GD Sher - Transfusion Medicine …, 2001 - Elsevier
C ANADA has recently implemented the uni-versal reduction of all blood components, making
it one of the first countries to implement this important safety enhancement. Although it is …
it one of the first countries to implement this important safety enhancement. Although it is …
Hydroxyurea use during pregnancy: a case report in sickle cell disease and review of the literature
O Diav‐Citrin, L Hunnisett, GD Sher… - American journal of …, 1999 - Wiley Online Library
A patient being treated for sickle cell disease with hydroxyurea (1 g/d) conceived, and drug
treatment was discontinued at nine weeks gestational age. The pregnancy and delivery were …
treatment was discontinued at nine weeks gestational age. The pregnancy and delivery were …
