Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Background Medicinal cannabinoids, including medicinal cannabis and pharmaceutical
cannabinoids and their synthetic derivatives, such as tetrahydrocannabinol (THC) and …

Background This review is one of a series on drugs used to treat chronic neuropathic pain.
Estimates of the population prevalence of chronic pain with neuropathic components range …

This review examines evidence for the effectiveness of cannabinoids in chronic noncancer
pain (CNCP) and addresses gaps in the literature by: considering differences in outcomes …

Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Background: Cannabis is increasingly available for the treatment of chronic pain, yet its
efficacy remains uncertain. Purpose: To review the benefits of plant-based cannabis …

Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

Cannabis, or marijuana, has been used for medicinal purposes for many years. Several
types of cannabinoid medicines are available in the U nited S tates and C anada …

BACKGROUND: The management of chronic pain is a complex challenge worldwide.
Cannabis-based medicines (CBMs) have proven to be efficient in reducing chronic pain …

Background Cannabis sativa has been cultivated throughout human history as a source of
fiber, oil and food, and for its medicinal and intoxicating properties. Selective breeding has …