[HTML][HTML] Modeling Parkinson's disease with the alpha-synuclein protein
M Gómez-Benito, N Granado, P García-Sanz… - Frontiers in …, 2020 - frontiersin.org
Alpha-synuclein (α-Syn) is a key protein involved in Parkinson's disease (PD) pathology. PD
is characterized by the loss of dopaminergic neuronal cells in the substantia nigra pars …
is characterized by the loss of dopaminergic neuronal cells in the substantia nigra pars …
[HTML][HTML] Biomedical applications and bioavailability of curcumin—An updated overview
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …
identified as the bioactive compound responsible for numerous pharmacological activities of …
[HTML][HTML] Potential role of ginger (Zingiber officinale Roscoe) in the prevention of neurodegenerative diseases
Ginger is composed of multiple bioactive compounds, including 6-gingerol, 6-shogaol, 10-
gingerol, gingerdiones, gingerdiols, paradols, 6-dehydrogingerols, 5-acetoxy-6-gingerol, 3 …
gingerol, gingerdiones, gingerdiols, paradols, 6-dehydrogingerols, 5-acetoxy-6-gingerol, 3 …
Metals associated neurodegeneration in Parkinson's disease: Insight to physiological, pathological mechanisms and management
Parkinson's disease (PD) is a deliberately progressive neurological disorder, arises due to
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The …
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The …
[HTML][HTML] Cannabidiol for neurodegenerative disorders: A comprehensive review
Despite the significant advances in neurology, the cure for neurodegenerative conditions
remains a formidable task to date. Among various factors arising from the complex etiology …
remains a formidable task to date. Among various factors arising from the complex etiology …
[HTML][HTML] Neurodegenerative diseases: Regenerative mechanisms and novel therapeutic approaches
Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
[HTML][HTML] Clinical features of Parkinson's disease: the evolution of critical symptoms
C Váradi - Biology, 2020 - mdpi.com
Parkinson's disease (PD) is a multi-attribute neurodegenerative disorder combining motor
and nonmotor symptoms without well-defined diagnostic clinical markers. The presence of …
and nonmotor symptoms without well-defined diagnostic clinical markers. The presence of …
iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates
Young-onset Parkinson's disease (YOPD), defined by onset at< 50 years, accounts for
approximately 10% of all Parkinson's disease cases and, while some cases are associated …
approximately 10% of all Parkinson's disease cases and, while some cases are associated …
[HTML][HTML] GaborPDNet: Gabor transformation and deep neural network for Parkinson's disease detection using EEG signals
Parkinson's disease (PD) is globally the most common neurodegenerative movement
disorder. It is characterized by a loss of dopaminergic neurons in the substantia nigra of the …
disorder. It is characterized by a loss of dopaminergic neurons in the substantia nigra of the …
Advancement in the modelling and therapeutics of Parkinson's disease
SN Rai, P Singh - Journal of chemical neuroanatomy, 2020 - Elsevier
Since the discovery of L-dopa in the middle of the 20th century (1960s), there is not any
neuroprotective therapy available although significant development has been made in the …
neuroprotective therapy available although significant development has been made in the …