Infant gliomas have paradoxical clinical behavior compared to those in children and adults:
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …

A retrospective study was performed to collect information regarding efficacy and toxicity of
cidofovir (CDV) in allogeneic stem cell transplant patients. Data were available on 82 patients…

Infant gliomas have paradoxical clinical behavior compared to those in children and adults:
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …

PURPOSE Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer
predisposition syndrome characterized by early-onset synchronous and metachronous …

Introduction Supratentorial primitive neuroectodermal tumors (SPNET) are rare tumors
accounting for only 2.5% of childhood brain tumors. The purpose of this study was to describe the …

Replication repair deficiency (RRD) leading to hypermutation is an important driving
mechanism of high-grade glioma (HGG) occurring predominantly in the context of germline …

BACKGROUND Most reported data of chemoradiotherapy protocols for the treatment of
medulloblastoma describe children who were treated in the first decade of life. To consider the …

Background Choroid plexus tumors (CPT) are rare pediatric tumors. A population-based study
on choroid plexus carcinoma (CPC) and choroid plexus papilloma (CPP) was carried out …

Mismatch repair (MMR) is a critical defence against mutation, but we lack quantification of
its activity on different DNA lesions during human life. We performed whole-genome …

Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential
to understand treatment trends to interpret national survival data. In Canada, children with …