Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which acceptable …

Viral respiratory tract infections are the main causative agents of the onset of infection-induced
asthma and asthma exacerbations that remain mechanistically unexplained. Here we …

BACKGROUND: Otitis media with effusion (OME) is a chronic inflammatory disease of the
middle ear space characterized by the accumulation of fluid. Previous investigations have …

Background Intravenous immunoglobulin (IVIg) is a polyclonal IgG preparation with potent
immunomodulating properties. Our laboratory demonstrated that IVIg significantly increases …

In the course of screening immunoglobulin G (IgG) sequences for T cell epitopes, we identified
novel Treg epitope peptides, now called Tregitopes, contained in the highly conserved …

Population-level immune surveillance, which includes monitoring exposure and assessing
vaccine-induced immunity, is a crucial component of public health decision-making during a …

Eight pediatric patients with severe steroid-dependent asthma were enrolled in an open-label
trial of high-dose intravenous immunoglobulin (IVIG) in an attempt to decrease their …

Intravenous immunoglobulin (IVIG) is the mainstay of therapy for humoral immune deficiencies
and numerous inflammatory disorders. Although the use of IVIG may be supplanted by …

In brief Immune dysfunction may contribute to or cause recurrent implantation failure. This
article summarizes normal and pathologic immune responses at implantation and critically …

BACKGROUND: Our laboratory has demonstrated previously that human tonsillar B lymphocytes
express IL-13 mRNA OBJECTIVE: We sought to investigate IL-13 production by human …