User profiles for Derek R. Stein

Derek Riley Stein

Cadham Provincial Laboratory
Verified email at gov.mb.ca
Cited by 1228

Evaluation of Euroimmun anti-Zika virus IgM and IgG enzyme-linked immunosorbent assays for Zika virus serologic testing

…, S Hung, CF Wong, DR Stein, R Olsha… - Journal of clinical …, 2017 - Am Soc Microbiol
With the emerging Zika virus (ZIKV) epidemic, serologic diagnosis relies on a labor-intensive
IgM antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) and confirmation …

[HTML][HTML] DNA vaccination protects mice against Zika virus-induced damage to the testes

…, A Majer, M Hagan, J Audet, DR Stein… - Nature …, 2017 - nature.com
Zika virus (ZIKV) is an emerging pathogen causally associated with serious sequelae in
fetuses, inducing fetal microcephaly and other neurodevelopment defects. ZIKV is primarily …

[HTML][HTML] Evaluation of 5 commercially available Zika virus immunoassays

D Safronetz, A Sloan, DR Stein… - Emerging infectious …, 2017 - ncbi.nlm.nih.gov
Because of the global spread of Zika virus, accurate and high-throughput diagnostic
immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available …

Current research for a vaccine against Lassa hemorrhagic fever virus

BM Warner, D Safronetz, DR Stein - Drug design, development and …, 2018 - Taylor & Francis
Lassa virus (LASV) is a rodent-borne arenavirus endemic to several West African countries
that causes Lassa fever (LF). LF is typically mild but it can cause severe disease …

[HTML][HTML] Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison

…, J Papenburg, MP Cheng, P Chakraborty, DR Stein… - PloS one, 2021 - journals.plos.org
The true severity of infection due to COVID-19 is under-represented because it is based on
only those who are tested. Although nucleic acid amplifications tests (NAAT) are the gold …

[HTML][HTML] A recombinant vesicular stomatitis-based Lassa fever vaccine elicits rapid and long-term protection from lethal Lassa virus infection in guinea pigs

DR Stein, BM Warner, G Soule, K Tierney, KL Frost… - npj Vaccines, 2019 - nature.com
The World Health Organization has identified Lassa virus (LASV) as one of the top five
pathogens to cause a severe outbreak in the near future. This study assesses the ability of a …

Nanobodies: a new approach for the diagnosis and treatment of viral infectious diseases

P Sroga, D Safronetz, DR Stein - Future Virology, 2020 - Future Medicine
With the rise of viral infections and antibiotic resistance, there is a constant need for the
development of more sensitive and effective treatment and diagnostic tools. Since their discovery …

[HTML][HTML] Simulated sunlight decreases the viability of SARS-CoV-2 in mucus

…, M Chan, J Audet, A Leung, D Kobasa, DR Stein… - PloS one, 2021 - journals.plos.org
The novel coronavirus, SARS-CoV-2, has spread into a pandemic since its emergence in
Wuhan, China in December of 2019. This has been facilitated by its high transmissibility within …

[HTML][HTML] Differential pathogenesis of closely related 2018 Nigerian outbreak clade III Lassa virus isolates

DR Stein, BM Warner, J Audet, G Soule… - PLoS …, 2021 - journals.plos.org
Nigeria continues to experience ever increasing annual outbreaks of Lassa fever (LF). The
World Health Organization has recently declared Lassa virus (LASV) as a priority pathogen …

[HTML][HTML] Vesicular stomatitis virus-based vaccines provide cross-protection against andes and sin nombre viruses

BM Warner, DR Stein, RK Jangra, MM Slough, P Sroga… - Viruses, 2019 - mdpi.com
Andes virus (ANDV) and Sin Nombre virus (SNV) are the main causative agents responsible
for hantavirus cardiopulmonary syndrome (HCPS) in the Americas. HCPS is a severe …