The recommendations listed in this CPG are, whenever possible, evidence based. In April
2013, an extensive evidence review was conducted, which included a literature review …

Objective To describe rates and risk factors for prolonged postoperative use of opioids in
patients who had not previously used opioids and undergoing major elective surgery. Design …

Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue.
Lacking effective therapies, risk factor modification may offer a means of preventing this …

Background: Intraoperative hypotension (IOH) may be associated with postoperative acute
kidney injury (AKI), but the duration of hypotension for triggering harm is unclear. The authors …

PURPOSE: To investigate the effects of α 2 -adrenergic agonists on perioperative mortality
and cardiovascular complications in adults undergoing surgery. METHODS: MEDLINE (1966 …

Background: The Revised Cardiac Risk Index (RCRI) is widely used to predict perioperative
cardiac complications. Purpose: To evaluate the ability of the RCRI to predict cardiac …

Background Preoperative anemia is an important risk factor for perioperative red blood cell
transfusions and has been shown to be independently associated with adverse outcomes …

Background— Preoperative anemia is an important risk factor for perioperative red blood
cell transfusions, which are associated with postoperative morbidity and mortality. Whether …

BACKGROUND: Although the association between massive perioperative blood loss (MBL)
and adverse outcomes is well recognized, it is unclear whether MBL is an independent risk …

BACKGROUND: Many clinical trials have demonstrated the effectiveness of gabapentin and
pregabalin administration in the perioperative period as an adjunct to reduce acute …