User profiles for Dylan S. MacKay

Dylan S. MacKay

University of Manitoba
Verified email at umanitoba.ca
Cited by 1648

Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies

…, MM Jeyaraman, AE Reid, M Fiander, DS MacKay… - Cmaj, 2017 - Can Med Assoc
BACKGROUND Nonnutritive sweeteners, such as aspartame, sucralose and stevioside, are
widely consumed, yet their long-term health impact is uncertain. We synthesized evidence …

Phytosterols in human nutrition: Type, formulation, delivery, and physiological function

DS MacKay, PJH Jones - European Journal of Lipid Science …, 2011 - Wiley Online Library
Phytosterols are a family of compounds similar to cholesterol which have been shown to
lower cholesterol levels when supplemented in the diet. A daily dose of 2–3 g of phytosterols …

Early exposure to nonnutritive sweeteners and long-term metabolic health: a systematic review

…, A Mann, AM Abou-Setta, M Fiander, DS MacKay… - …, 2016 - publications.aap.org
OBJECTIVE: To synthesize evidence from prospective studies evaluating the association of
early-life NNS exposure and long-term metabolic health. DATA SOURCES: Medline, Embase…

Progress and perspectives in plant sterol and plant stanol research

PJH Jones, M Shamloo, DS MacKay… - Nutrition …, 2018 - academic.oup.com
Current evidence indicates that foods with added plant sterols or stanols can lower serum
levels of low-density lipoprotein cholesterol. This review summarizes the recent findings and …

Methodological considerations for the harmonization of non-cholesterol sterol bio-analysis

DS Mackay, PJH Jones, SB Myrie, J Plat… - … of chromatography B, 2014 - Elsevier
Non-cholesterol sterols (NCS) are used as surrogate markers of cholesterol metabolism
which can be measured from a single blood sample. Cholesterol precursors are used as …

Effect of sucralose and aspartame on glucose metabolism and gut hormones

SY Ahmad, JK Friel, DS Mackay - Nutrition Reviews, 2020 - academic.oup.com
Non-nutritive sweeteners are thought to be useful replacements for caloric sweeteners in
sweet food and beverages, since the reduction in energy and carbohydrate intake may lead to …

High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans

PJH Jones, DS MacKay, VK Senanayake, S Pu… - Atherosclerosis, 2015 - Elsevier
… Author links open overlay panel Peter JH Jones a , Dylan S. MacKay a , Vijitha K.
Senanayake a , Shuaihua Pu a , David JA Jenkins b , Philip W. Connelly b , Benoît Lamarche c , …

The effect of the artificial sweeteners on glucose metabolism in healthy adults: a randomized, double-blinded, crossover clinical trial

SY Ahmad, JK Friel, DS MacKay - Applied Physiology, Nutrition …, 2020 - cdnsciencepub.com
This study aimed to determine the effect of pure forms of sucralose and aspartame, in doses
reflective of common consumption, on glucose metabolism. Healthy participants consumed …

[HTML][HTML] CYP7A1-rs3808607and APOEisoform associate with LDL cholesterol lowering after plant sterol consumption in a randomized clinical trial

DS MacKay, PK Eck, SK Gebauer, DJ Baer… - The American journal of …, 2015 - Elsevier
Background:The benefits of plant sterols (PSs) for cholesterol lowering are hampered by large
heterogeneity across individuals, potentially because of genetic polymorphisms. Objective…

[HTML][HTML] First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas-and liquid-chromatography–Urgent …

…, V Leoni, AM Lottenberg, DS MacKay, S Matysik… - The Journal of steroid …, 2019 - Elsevier
Serum concentrations of lathosterol, the plant sterols campesterol and sitosterol and the
cholesterol metabolite 5α-cholestanol are widely used as surrogate markers of cholesterol …