MDR1 (P‐glycoprotein) is an important factor in the disposition of many drugs, and the
involved processes often exhibit considerable interindividual variability that may be genetically …

Drug interactions occur when the efficacy or toxicity of a medication is changed by administration
of another substance. Pharmacokinetic interactions often occur as a result of a change …

Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis,
assessment, prevention, and treatment of hypertension in adults and children. This year, …

Objectives Our objective was to examine the effect of different fruits and their constituents on
P‐glycoprotein and organic anion transporting polypeptide (OATP) activities in vitro and on …

Hypertension Canada's Canadian Hypertension Education Program Guidelines Task Force
provides annually updated, evidence-based recommendations to guide the diagnosis, …

The Canadian Hypertension Education Program reviews the hypertension literature annually
and provides detailed recommendations regarding hypertension diagnosis, assessment, …

Hypertension Canada’s 2020 guidelines for the prevention, diagnosis, risk assessment, and
treatment of hypertension in adults and children provide comprehensive, evidence-based …

Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis,
assessment, prevention, and treatment of hypertension. This year, we introduce 10 new …

Herein, updated evidence-based recommendations for the diagnosis, assessment, prevention,
and treatment of hypertension in Canadian adults are detailed. For 2014, 3 existing …

Background Myocardial injury after non-cardiac surgery (MINS) increases the risk of
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …