We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–associated
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …

Varicella-zoster virus (VZV), the cause of chickenpox and zoster, was the first human herpesvirus
to be sequenced fully and the first for which vaccines have been licensed and widely …

Cirrhosis and hepatocellular carcinoma occur as long‐term complications of chronic
hepatitis B virus (HBV) infection. Antiviral therapy is potentially a successful approach for the …

… Graham Tipples, head of viral exanthematac, … Best JM, O'Shea S, Tipples G, Davies N,
Al-Khusaiby SM, Krause A et al. … Articles by Graham Tipples …

The (–) enantiomer of 3′–thiacytidine (lamivudine) has been found to be a potent inhibitor
of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) replication. Mutation of …

Background COVID-19 is diagnosed via detection of SARS-CoV-2 RNA using real time
reverse-transcriptase polymerase chain reaction (rtRT-PCR). Performance of many SARS-CoV-2 …

We have developed a single-tube assay for SARS-CoV-2 in patient samples. This assay
combined advantages of reverse transcription (RT) loop-mediated isothermal amplification (…

By analysis of a single, variable, and short DNA sequence of 447 bp located within open
reading frame 22 (ORF22), we discriminated three major varicella-zoster virus (VZV) genotypes…

CRISPR-Cas systems integrated with nucleic acid amplification techniques improve both
analytical specificity and sensitivity. We describe here issues and solutions for the successful …

Coronavirus disease (COVID) serological tests are essential to determine the overall
seroprevalence of a population and to facilitate exposure estimates within that population. We …