User profiles for John D. O‚Neil

John D O'Neil

Professor, Simon Fraser University
Verified email at sfu.ca
Cited by 5697

Identifying indigenous peoples for health research in a global context: a review of perspectives and challenges

…, L Madariaga-Vignudo, JD O'Neil… - … journal of …, 2007 - Taylor & Francis
Objectives. Identifying Indigenous Peoples globally is complex and contested despite there
being an estimated 370 million living in 70 countries. The specific context and use of locally …

Have investments in on-reserve health services and initiatives promoting community control improved First Nations' health in Manitoba?

…, T Prakash, M Dahl, P Martens, JD O'Neil - Social science & …, 2010 - Elsevier
The objective of this study was to document the relationship between First Nation’s community
characteristics and the rates of hospitalization for Ambulatory Care Sensitive Conditions (…

Epstein–Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro

JD O'Neil, TJ Owen, VHJ Wood… - Journal of General …, 2008 - microbiologyresearch.org
The Epstein–Barr virus (EBV)-encoded EBNA1 protein is expressed in all virus-associated
tumours, including nasopharyngeal carcinoma (NPC), where it plays an essential role in EBV …

[HTML][HTML] Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

…, SP Maia, J Shao, JR Arrand, LS Young, JD O'Neil - Molecular cancer, 2010 - Springer
Background The Epstein-Barr virus (EBV)-encoded EBNA1 protein is expressed in all EBV-associated
tumours, including undifferentiated nasopharyngeal carcinoma (NPC), where it is …

Cooptation and control: The reconstruction of Inuit birth

PA Kaufert, JD O'Neil - Medical Anthropology Quarterly, 1990 - Wiley Online Library
In this article we explore the implications for obstetric policies and practice of methods of
recording, retrieving, and evaluating information. More particularly, we are concerned with the …

[HTML][HTML] Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and …

…, HE Cunliffe, EA Ross, DR Rosner, JD O'neil… - Scientific reports, 2017 - nature.com
In many different cell types, pro-inflammatory agonists induce the expression of cyclooxygenase
2 (COX-2), an enzyme that catalyzes rate-limiting steps in the conversion of arachidonic …

Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48

…, G Bottegoni, JD O'Neil, T Major, D Griffin… - Science …, 2021 - science.org
Dysregulated mitochondrial function is a hallmark of immune-mediated inflammatory
diseases. Cytochrome c oxidase (CcO), which mediates the rate-limiting step in mitochondrial …

[HTML][HTML] Dominant suppression of inflammation via targeted mutation of the mRNA destabilizing protein tristetraprolin

EA Ross, T Smallie, Q Ding, JD O'Neil… - The Journal of …, 2015 - journals.aai.org
In myeloid cells, the mRNA-destabilizing protein tristetraprolin (TTP) is induced and
extensively phosphorylated in response to LPS. To investigate the role of two specific …

Cardiovascular diseases in a Canadian Arctic population.

TK Young, ME Moffatt, JD O'Neil - American Journal of …, 1993 - ajph.aphapublications.org
OBJECTIVES. The purpose of this study was to review cardiovascular mortality, morbidity,
and risk factors in the multiethnic population of the Northwest Territories, Canada. METHODS. …

[HTML][HTML] Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts

T Crowley, JD O'neil, H Adams, AM Thomas… - Arthritis research & …, 2017 - Springer
Background It has been hypothesized that chronic inflammatory diseases such as rheumatoid
arthritis (RA) may be caused by a failure of negative feedback mechanisms. This study …