[HTML][HTML] Enhancing adult nerve regeneration through the knockdown of retinoblastoma protein

KJ Christie, A Krishnan, JA Martinez, K Purdy… - Nature …, 2014 - nature.com
Tumour suppressor pathways may offer novel targets capable of altering the plasticity of post-mitotic
adult neurons. Here we describe a role for the retinoblastoma (Rb) protein, widely …

A BRCA1-dependent DNA damage response in the regenerating adult peripheral nerve milieu

A Krishnan, K Purdy, A Chandrasekhar… - Molecular …, 2018 - Springer
It is not generally appreciated that DNA repair machinery has a critical role in the remodeling
of neurons that adopt a regenerative phenotype. We identified that breast cancer 1 (BRCA1)…

[HTML][HTML] Case report: COVID-19 infection and cervical artery dissection

K Purdy, R Long, G Jickling - The American Journal of Tropical …, 2022 - ncbi.nlm.nih.gov
A 45-year-old woman presented 3 days after symptom resolution from a COVID-19 infection
with a left vertebral artery dissection with no known preceding trauma or underlying …

The clinical conundrum of managing ischemic stroke in patients with immune thrombocytopenia

A Alrohimi, K Purdy, M Alqarni, G Alotaibi… - Canadian Journal of …, 2021 - cambridge.org
Guidelines are lacking for management of acute ischemic stroke and stroke prevention in
patients with immune thrombocytopenia (ITP). Our aim is to highlight the dilemma inherent in …

[HTML][HTML] Unmatched Canadian medical graduates

SL Silverberg, KMH Purdy - CMAJ, 2018 - Can Med Assoc
The Canadian residency match is high stakes for Canadian medical students, as it is the
only in-country route into clinical practice for Canadian medical graduates. There is an …

[HTML][HTML] Can osmotic demyelination syndrome be a complication of liver failure?

K Purdy, D Anderson, R Camicioli, RG Khadaroo - Eneurologicalsci, 2020 - Elsevier
This case demonstrates that osmotic demyelination syndrome (ODS) can occur in absence
of hyponatremia in patients with fulminant liver failure and markedly high bilirubin levels. …

Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis with Microscopic Thymoma

A Banerjee, N Nathoo, K Purdy, K Puznak… - Canadian Journal of …, 2023 - cambridge.org
Myasthenia gravis (MG) is an antibody-mediated disorder of the neuromuscular junction
characterized by fatigable weakness. The majority of patients with MG are found to have …

[HTML][HTML] My brother

K Purdy - CMAJ, 2021 - Can Med Assoc
My oldest brother, Blake, was six years my senior. Despite our age difference, he never
made me feel like his annoying little sister. He taught me how to tie my shoes when I was four …

An Effectiveness Analysis of Walk-in Stroke Centres in Northern Alberta (S20. 001)

K Purdy, T Jeerakathil, D Owens, E Bendavid - 2023 - AAN Enterprises
Objective: To model the effectiveness of walk-in stroke centres (WSCs) in acute stroke care.
Background: Access to thrombolytics for people experiencing acute stroke symptoms …

The neurology residents of COVID-19

K Purdy - neurology, 2020 - AAN Enterprises
Residents are the backbone of medical systems across the world. When coronavirus 2019
(COVID-19) arrived, neurology training programs were disrupted, but without hesitation …