User profiles for M. Neil Reaume

Martin Neil Reaume

Verified email at toh.on.ca
Cited by 4164

[HTML][HTML] Enzalutamide with standard first-line therapy in metastatic prostate cancer

…, W Parulekar, DW Pook, MN Reaume… - … England Journal of …, 2019 - Mass Medical Soc
Background Enzalutamide, an androgen-receptor inhibitor, has been associated with improved
overall survival in men with castration-resistant prostate cancer. It is not known whether …

[HTML][HTML] Rucaparib or physician's choice in metastatic prostate cancer

K Fizazi, JM Piulats, MN Reaume… - … England Journal of …, 2023 - Mass Medical Soc
Background In a phase 2 study, rucaparib, an inhibitor of poly(ADP-ribose) polymerase (PARP),
showed a high level of activity in patients who had metastatic, castration-resistant …

[HTML][HTML] Randomized phase III trial of adjuvant pazopanib versus placebo after nephrectomy in patients with localized or locally advanced renal cell carcinoma

…, M Zemanova, LA Wood, MN Reaume… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
M. Neil Reaume … Suttle AB, Ball HA, Molimard M, et al.: Relationships between
pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell …

Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis

…, B Hemmelgarn, T Reiman, B Manns, MN Reaume… - Cmaj, 2009 - Can Med Assoc
Background: Erythropoiesis-stimulating agents are used to treat anemia in patients with
cancer. However, their safety and effectiveness is controversial. We did a systematic review of …

Evaluation of clear cell, papillary, and chromophobe renal cell carcinoma metastasis sites and association with survival

…, N Kroeger, R Kanesvaran, MN Reaume… - JAMA network …, 2021 - jamanetwork.com
Importance There exists considerable biological and clinical variability between histologic
variants of metastatic renal cell carcinoma (mRCC). Data reporting on patterns of metastasis …

[HTML][HTML] Effect of chemotherapy with docetaxel with androgen suppression and radiotherapy for localized high-risk prostate cancer: the randomized phase III NRG …

…, GB Rodrigues, L Souhami, MN Reaume… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE Radiotherapy (RT) plus long-term androgen suppression (AS) are a standard
treatment option for patients with high-risk localized prostate cancer. We hypothesized that …

Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study

…, E Winquist, C Elser, A Eisen, MN Reaume… - The lancet …, 2013 - thelancet.com
Background No standard treatment exists for patients with platinum-refractory urothelial
cancer. Taxanes and vinflunine are commonly used, but response is less than 20% with no …

A phase III protocol of androgen suppression (AS) and 3DCRT/IMRT versus AS and 3DCRT/IMRT followed by chemotherapy (CT) with docetaxel and prednisone for …

…, AG Balogh, G Rodrigues, L Souhami, MN Reaume… - 2015 - ascopubs.org
LBA5002 Background: High-risk, localized prostate cancer (PCa) patients have a relatively
poor prognosis. We hypothesized that the addition of adjuvant docetaxel and prednisone to …

Adjuvant pazopanib versus placebo after nephrectomy in patients with localized or locally advanced renal cell carcinoma: final overall survival analysis of the phase 3 …

…, B Rini, TK Choueiri, L Wood, MN Reaume… - European urology, 2021 - Elsevier
M. Neil Reaume has received consulting fees/honoraria from Bayer, Pfizer, BristolMyers
Squibb, AstraZeneca, Novartis, Eisai, Ipsen, Merck, and Roche; and is a consultant for Astellas. …

Overall survival of men with metachronous metastatic hormone-sensitive prostate cancer treated with enzalutamide and androgen deprivation therapy

…, F Parnis, W Parulekar, DW Pook, MN Reaume… - European Urology, 2021 - Elsevier
Men who initially present with localized prostate cancer and later develop metachronous
metastases have a better prognosis than men with de novo metastatic disease and often have …