Opioid use disorder continues to be a significant source of morbidity and mortality in the
USA and the world. Pharmacologic treatment with methadone and buprenorphine has been …

Fentanyl Overdose and Acute Amnestic Syndrome A syndrome of severe amnesia and
medial temporal changes on magnetic resonance imaging after drug overdose has been …

Methods All closed cases of ingestions involving children aged≤ 19 years reported to US
poison control centers from March 13 to December 31, 2020 (pandemic), were compared with …

Importance Opioid-reduction policies have been enacted by US states to address the opioid
epidemic. Evidence of an association between policy implementation and decreased rates …

Context: Exploratory buprenorphine ingestions in young children have been associated
with clinically significant toxicity. However, detailed data on the clinical presentation and …

Methods| In this cohort study, we analyzed health care claims from a nationwide commercial
health insurance plan covering 9 338 501 adolescents (aged 13-18 years) and young …

Introduction Prescription drug monitoring programs are state-run databases designed to
support safe prescribing of controlled substances and reduce prescription drug misuse. We …

Background: Methadone is a synthetic μ-opioid receptor agonist that is used in the management
of pain, neonatal abstinence withdrawal syndrome, and opioid dependence. Overdose …

Background Exploratory pediatric cannabis poisonings are increasing. The aim of this study
is to provide a national assessment of the frequency and trends of diagnostic testing and …

Many reports of marijuana-associated myocardial infarct (MI) are limited by incomplete
evaluation of the toxicologic exposure, a lack of definitive anatomic findings, and the potential for …