Pannexin-1 (Px1) is expressed at postsynaptic sites in pyramidal neurons, suggesting that
these hemichannels contribute to dendritic signals associated with synaptic function. We …

TRPM2 is a Ca 2+ ‐permeable member of the transient receptor potential melastatin family
of cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and …

Background: Health care office staff and providers may discriminate against people of low
socioeconomic status, even in the absence of economic incentives to do so. We sought to …

Access to essential medications and health products is critical to effective management of
kidney disease. Using data from the ISN Global Kidney Health Atlas multinational cross-…

Exposure to low Ca 2+ and/or Mg 2+ is tolerated by cardiac myocytes, astrocytes, and neurons,
but restoration to normal divalent cation levels paradoxically causes Ca 2+ overload and …

Optimal kidney care requires a trained nephrology workforce, essential healthcare services,
and medications. This study aimed to identify the access to these resources on a global …

An international survey led by the International Society of Nephrology in 2016 assessed the
current capacity of kidney care worldwide. To better understand how governance and …

Introduction Fasting during the month of Ramadan is a significant Islamic religious practice
that involves abstinence from food, drink and medication from dawn to dusk. As just under a …

Importance The clinical management ofBRCA1andBRCA2mutation carriers requires accurate,
prospective cancer risk estimates. Objectives To estimate age-specific risks of breast, …

The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported
in single populations, with the majority of reports focused on White in Europe and North …