Objective To determine the efficacy of high dose folic acid supplementation for prevention of
pre-eclampsia in women with at least one risk factor: pre-existing hypertension, …

Objective To summarize information on the maternal and perinatal outcomes among pregnant
women with a maternal age greater or equal to 45 years old compared with women with a …

Obesity is a well-recognized risk factor for pregnancy complications. Most studies to date are
in large cohorts, with results presented in a way that assumes all women living with obesity …

Multiple clinical practice guidelines (CPGs) have been established for pregnant women with
obesity. The quality and consistency of recommendations remain unknown. The objective of …

Background: Maternal obesity is associated with stillbirth, but uncertainty persists around the
effects of higher obesity classes. We sought to compare the risk of stillbirth associated with …

Background Periconceptional folic acid (FA) supplementation is recommended to prevent
the occurrence of neural tube defects. Currently, most over-the-counter FA supplements in …

Background Low-dose aspirin is recommended for pregnant individuals at high-risk of
developing preeclampsia, but less is known about those that develop preeclampsia even while …

Objective To determine the efficacy of high-dose folic acid for the prevention of preeclampsia
in twin pregnancies. Methods Secondary analysis of a randomized controlled trial in 70 …

Introduction FACT is an international, multi-centre, double-blind, placebo-controlled, Phase
III trial of 3656 women, sponsored by the Ottawa Hospital Research Institute (OHRI) and …

Objectives To determine the efficacy of high dose folic acid supplementation for prevention
of preeclampsia in women with at least one of these risk factors: pre-existing hypertension, …