Pre-clinical models have shown that targeting pancreatic stellate cells with all-trans-retinoic-acid
(ATRA) reprograms pancreatic stroma to suppress pancreatic ductal adenocarcinoma (…

A major public health concern of cannabis legalization is that it may result in an increase in
psychotic disorders. We examined changes in emergency department (ED) visits for cannabis…

Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with
around 9% of patients surviving >5 years. Asymptomatic in its initial stages, PDAC is mostly …

Perhaps the most important feature of neutrophils is their ability to rapidly change shape. In
the bloodstream, the neutrophils circulate as almost spherical cells, with the ability to deform …

Importance Prior research suggests that the legalization of recreational cannabis is associated
with increases in cannabis hyperemesis syndrome (CHS), but it is unclear how cannabis …

Importance Problematic alcohol use in physicians poses a serious concern to physicians'
health and their ability to provide care. Understanding the extent and characteristics of …

Background: When patients and physicians speak the same language, it may improve the
quality and safety of care delivered. We sought to determine whether patient–physician …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. Its high
mortality rate is attributed largely to the difficulty of early diagnosis. Analysis of urine is an …

Background The Coronavirus Disease 2019 (COVID–19) pandemic has exacerbated mental
health challenges among physicians and non–physicians. However, it is unclear if the …

Background At the end of life, individuals may experience physical symptoms such as pain,
and guidelines recommend medications to manage these symptoms. Yet, little is known …