[PDF][PDF] The treatment-naive microbiome in new-onset Crohn's disease

…, R Baldassano, A Griffiths, F Sylvester, D Mack, S Kim… - Cell host & …, 2014 - cell.com
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked
to host pathways that implicate an underlying role for aberrant immune responses to …

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

JA Chong, J Tapia-Ramirez, S Kim, JJ Toledo-Aral… - Cell, 1995 - cell.com
Expression of the type II voltage-dependent sodium channel gene is restricted to neurons
by a silencer element active in nonneuronal cells. We have cloned cDNA coding for a …

Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria

SC Kim, SL Tonkonogy, CA Albright, J Tsang, EJ Balish… - Gastroenterology, 2005 - Elsevier
Background & Aims: To explore the hypothesis that selective immune responses to distinct
components of the intestinal microflora induce intestinal inflammation, we characterized …

[BOOK][B] Obstetrics and gynecology

SI Kim, TA Swanson, RC Chen - 2008 - books.google.com
Completely revised by new authors, this Fourth Edition presents 75 patient cases designed
specifically to prepare students for clinical vignettes on the USMLE Step 2. Each case …

The cost of inflammatory bowel disease: an initiative from the Crohn's & Colitis Foundation

…, EM Szigethy, K Henrichsen, SC Kim… - Inflammatory bowel …, 2020 - academic.oup.com
Background The Crohn’s & Colitis Foundation’s Cost of Inflammatory Bowel Disease (IBD)
Care Initiative seeks to quantify the wide-ranging health care costs affecting patients living …

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

A Shkoda, PA Ruiz, H Daniel, SC Kim, G Rogler… - Gastroenterology, 2007 - Elsevier
Background & Aims: The initiation of endoplasmic reticulum (ER)-mediated stress responses
in intestinal epithelial cells (IEC) may contribute to the pathogenesis of chronic intestinal …

Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation

N Steck, M Hoffmann, IG Sava, SC Kim, H Hahne… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Matrix metalloproteases (MMPs) mediate pathogenesis of chronic
intestinal inflammation. We characterized the role of the gelatinase (GelE), a metalloprotease …

Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease

…, L Duffy, F Del Rosario, SC Kim… - Inflammatory bowel …, 2011 - Wiley Online Library
Background: Obesity is a significant public health threat to children in the United States. The
aims were to: 1) Determine the prevalence of obesity in a multicenter cohort of children with …

Inflammatory bowel diseases in pediatric and adolescent patients: clinical, therapeutic, and psychosocial considerations

SC Kim, GD Ferry - Gastroenterology, 2004 - Elsevier
Inflammatory bowel diseases (Crohn’s disease and ulcerative colitis) primarily affect young
adults, but in 15%–25% of cases, the initial disease starts in childhood. Many aspects of …

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

TD Walters, MO Kim, LA Denson, AM Griffiths… - Gastroenterology, 2014 - Elsevier
Background & Aims Standard therapy for children newly diagnosed with Crohn's disease (CD)
includes early administration of immunomodulators after initial treatment with …