Novel synthetic opioids: an opioid epidemic within an opioid epidemic

SN Lucyk, LS Nelson - Annals of emergency medicine, 2017 - annemergmed.com
North America is currently facing an opioid epidemic. Opioid overdose deaths have increased
200% since 2000, and in 2014, 28,647 drug-poisoning deaths were attributed to some …

Management of acetaminophen poisoning in the US and Canada: a consensus statement

…, AI Stolbach, RG Hendrickson, SN Lucyk… - JAMA network …, 2023 - jamanetwork.com
Importance The US and Canada currently have no formal published nationwide guidelines
for specialists in poison information or emergency departments for the management of …

Methemoglobinemia caused by sodium nitrite overdose

D Saleh, S Lucyk, E McGillis - Cmaj, 2022 - Can Med Assoc
A 20-year-old man who was comatose and centrally cyanotic arrived at the emergency
department 1 hour after ingesting 21 g of sodium nitrite that was purchased online as part of a “…

Toxicosurveillance in the US opioid epidemic

SN Lucyk, LS Nelson - International Journal of Drug Policy, 2017 - Elsevier
The opioid epidemic presents an ever-changing epidemiological, clinical, and forensic
landscape that poses a significant challenge to regulators and legislators. Heroin is a long-…

Acute cardiovascular toxicity of cocaine

SN Lucyk - Canadian Journal of Cardiology, 2022 - Elsevier
Cocaine is one of the most commonly abused drugs and represents a major public health
concern. Cocaine users frequently present to the emergency department, with chest pain …

Patents, Politics and Public Health: Access to Essential Medicines Under the TRIPS Agreement

S Lucyk - Ottawa L. Rev., 2006 - HeinOnline
Patent law reflects a difficult balance between access and innovation. The HIV/AIDS pandemic
has raised global awareness of the social costs of patent protection and the need for …

Outcomes of patients with premature discontinuation of the 21-h intravenous N-acetylcysteine protocol after acute acetaminophen overdose

SN Lucyk, MC Yarema, MLA Sivilotti… - The Journal of …, 2016 - Elsevier
Background The minimum recommended treatment duration for iv N-acetylcysteine (NAC)
after an acute, single acetaminophen (APAP) overdose is 21 h. Some have questioned …

NMR conformational studies of micelle-bound orexin-B: a neuropeptide involved in the sleep/awake cycle and feeding regulation

M Miskolzie, S Lucyk, G Kotovych - Journal of Biomolecular …, 2003 - Taylor & Francis
The preferred conformation of orexin-B, an orphan G-protein coupled receptor agonist (the
human sequence is RSGPPGLQGRLQRLLQASGNHAAGILTM-NH 2 ) has been determined …

[HTML][HTML] Consequences of unsafe prescribing of transdermal fentanyl

S Lucyk, L Nelson - Cmaj, 2016 - Can Med Assoc
CMAJ, June 14, 2016, 188 (9) 639 although fluctuations may occur up to 72 hours after
initiation. 2, 7 This delay to onset and peak is due to the need for the applied fentanyl to traverse …