Background— C-reactive protein (CRP) has been suggested to actively participate in the
development of atherosclerosis. In the present study, we examined the role of the potent …

Hemostasis encompasses a set of tightly regulated processes that govern blood clotting,
platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates a …

Background Sodium–glucose cotransporter 2 inhibitors reduce the risk of hospitalization for
heart failure in patients with heart failure and a reduced ejection fraction, but their effects in …

Background In patients with type 2 diabetes, inhibitors of sodium–glucose cotransporter 2 (SGLT2)
reduce the risk of a first hospitalization for heart failure, possibly through glucose-…

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization
for heart failure in patients regardless of the presence or absence of diabetes. More …

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization
for heart failure or death from cardiovascular causes among patients with stable heart …

Case presentation 1: Mr Gundry is a 42-year-old construction worker who has had type II
diabetes mellitus for the past 6 years. He has no other vascular risk factors and is currently …

Sodium–glucose cotransporter (SGLT)2 inhibitors have been demonstrated to reduce
cardiovascular events, particularly heart failure, in cardiovascular outcome trials. Here, we review …

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization
for heart failure and cardiovascular death among patients with chronic heart failure …

Background Heart failure with preserved ejection fraction is increasing in prevalence and is
associated with a high symptom burden and functional impairment, especially in persons …