Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …

Natural killer T cells (NKT cells) represent a subset of T lymphocytes that express natural
killer (NK) cell surface markers. A subset of NKT cells, termed invariant NKT cells (iNKT), …

Klebsiella pneumoniae (Kp) is an important pathogen both in the community and the hospital
setting. In the community the emergence of virulent organisms with predominantly K1/K2 …

Vancomycin is one of the older antibiotics that has been now in clinical use close to 60 years.
Earlier on, vancomycin was associated with many side effects including vestibular and …

Community-acquired pyogenic liver abscess caused by Klebsiella pneumoniae is an emerging
infectious disease. We explored the capsular polysaccharide synthesis (cps) regions of …

Background The province of Ontario, Canada, has instituted indefinite school closures (SC)
as well as other social distancing measures to mitigate the impact of the novel coronavirus …

Background: Acute pulmonary edema has been noted in swimmers and divers, and has
been termed swimming-induced pulmonary edema (SIPE). The mechanisms and …

Severe influenza infection has no effective treatment available. One of the key barriers to
developing host-directed therapy is a lack of reliable prognostic factors needed to guide such …

Host response biomarkers can accurately distinguish between influenza and bacterial
infection. However, published biomarkers require the measurement of many genes, thereby …

Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus
aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this …