LONG-TERM REMISSION OF HIV-1 DISEASE CAN BE READILY ACHIEVED by
combinations of antiretroviral agents. The suppression of plasma viral loads to less than the …

Stavudine (d4T) has been observed in clinical trials and cohort studies to be more often
implicated in cases of hyperlactatemia than other nucleoside reverse transcriptase …

Purpose: Nucleoside reverse transcriptase inhibitors (NRTIs) are associated with
mitochondrial toxicities ranging from asymptomatic hyperlactatemia to fatal lactic acidosis. It …

When prescribed appropriately and taken adherently, antiretroviral therapy can consistently
and durably suppress HIV replication, potentially translating into years of near normal health …

Peripheral neuropathies (PN) are the most common neurodegenerative disease globally. A
variety of different insults lead to PN which include diabetes, cancer chemotherapy, and …

Discussion Global spread of the HIV epidemic has led to unprecedented advances in
antiviral chemotherapy [1]. During the past 5 years, options for antiretroviral therapy have …

Antiretroviral therapy (ART) has significantly improved the heath conditions of those living
with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). This …

The combined effect against human immunodeficiency virus (HIV) of oxanosine and 2′ 3′-
dideoxyinosine (ddI) has been evaluated by the production of viral particles, the expression …

Severe symptomatic hyperlactataemia and lactic acidosis (SHLA) are life-threatening events
that are occurring at increasing incidence levels in South Africa. Globally, the rise in SHLA …

A terapêutica anti-retrovírica constitui a verdadeira revolução na epidemiologia da infecção
VIH/SIDA. A adopção de regimes terapêuticos combinados permite um controlo mais …