The role for endoplasmic reticulum stress in diabetes mellitus

DL Eizirik, AK Cardozo, M Cnop - Endocrine reviews, 2008 - academic.oup.com
Accumulating evidence suggests that endoplasmic reticulum (ER) stress plays a role in the
pathogenesis of diabetes, contributing to pancreatic β-cell loss and insulin resistance …

Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis

CS Zipitis, AK Akobeng - Archives of disease in childhood, 2008 - adc.bmj.com
Objectives: To assess whether vitamin D supplementation in infancy reduces the risk of type
1 diabetes in later life. Methods: This was a systematic review and meta-analysis using …

Recent advances in smart hydrogels for biomedical applications: From self-assembly to functional approaches

NN Ferreira, LMB Ferreira, VMO Cardoso… - European Polymer …, 2018 - Elsevier
This review discusses basic aspects used to control the architecture and functional
properties of smart hydrogels. The introduction briefly outlines what has been accomplished …

A review on synthesis, mechanism of action, and structure-activity relationships of 1, 2, 3-triazole-based α-glucosidase inhibitors as promising anti-diabetic agents

Z Fallah, M Tajbakhsh, M Alikhani, B Larijani… - Journal of Molecular …, 2022 - Elsevier
Abstract α-Glucosidase is a key enzyme in hydrolysis of carbohydrates to glucose and
located in the small intestine brush border. Inhibition of this enzyme delay the release of …

TIGIT: An emerging immune checkpoint target for immunotherapy in autoimmune disease and cancer

J Zhao, L Li, H Yin, X Feng, Q Lu - International immunopharmacology, 2023 - Elsevier
Immune checkpoints (ICs), also referred to as co-inhibitory receptors (IRs), are essential for
regulating immune cell function to maintain tolerance and prevent autoimmunity. IRs, such …

Hypoglycemic agents and potential anti-inflammatory activity

V Kothari, JA Galdo, ST Mathews - Journal of inflammation …, 2016 - Taylor & Francis
Current literature shows an association of diabetes and secondary complications with
chronic inflammation. Evidence of these immunological changes include altered levels of …

Epigenetic modification and therapeutic targets of diabetes mellitus

R Singh, S Chandel, D Dey, A Ghosh, S Roy… - Bioscience …, 2020 - portlandpress.com
The prevalence of diabetes and its related complications are increasing significantly
globally. Collected evidence suggested that several genetic and environmental factors …

[HTML][HTML] In vitro and in vivo antidiabetic potential of monoterpenoids: An update

LT Al Kury, A Abdoh, K Ikbariah, B Sadek, M Mahgoub - Molecules, 2021 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic condition characterized by persistent
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …

Extraction and precipitation of phosphorus from sewage sludge

NC Shiba, F Ntuli - Waste Management, 2017 - Elsevier
Raw sewage sludge from East Rand Water Care Association (ERWAT) had high
phosphorus (P) content, approximately 15.2%(w/w) P 2 O 5, which indicates a potential …

Genetic and epigenetic factors in etiology of diabetes mellitus type 1

K Stankov, D Benc, D Draskovic - Pediatrics, 2013 - publications.aap.org
Diabetes mellitus type 1 (T1D) is a complex disease resulting from the interplay of genetic,
epigenetic, and environmental factors. Recent progress in understanding the genetic basis …