Few common conditions are surrounded by as much clinical uncertainty and diagnostic
mystery as pulmonary embolism. It may be silent, or it may be fatal, and clinicians are …

Importance of the field: The clinical suspicion of acute pulmonary embolism (PE) is
frequently raised. However, the diagnosis of PE is confirmed in only 20–30% of these …

The diagnosis of pulmonary embolism (PE) remains challenging despite the evolution of
well-validated clinical algorithms over the past few decades, largely because of nonspecific …

Background Current strategies for diagnosing pulmonary embolism include a clinical
decision rule (CDR), followed by a D-dimer assay in patients with an “unlikely” clinical …

Pulmonary embolism (PE) is a common, potentially life-threatening yet treatable condition.
Prompt diagnosis and expeditious therapeutic intervention is of paramount importance for …

• When pre-test probability is lower than the test threshold, risk of harm from testing is greater
than benefit from testing• Accuracy is not the sole measure of diagnostic performance• …

Acute venous thromboembolism (VTE) is a frequent and potentially fatal disorder with an
annual incidence of 0.2–0.6 per 1,000 [1, 2]. It remains a diagnostic challenge, because of …

A large and growing number of patients is evaluated at hospital emergency departments
each year because of clinically suspected pulmonary embolism (PE). The disease can be …

Diagnosing pulmonary embolism (PE) is challenging since clinical signs and symptoms are
non-specific. The diagnostic tests available for demonstrating PE all have their drawbacks …

The signs and symptoms of patients with pulmonary embolism (PE) form a wide spectrum
and considerably overlap with other cardiopulmonary diseases. Timely recognizing of this …