PT  - JOURNAL ARTICLE
AU  - Finley, J. P.
AU  - Collins, G. F.
AU  - de Chadarevian, J. P.
AU  - Williams, R. L.
TI  - DiGeorge syndrome presenting as severe congenital heart disease in the newborn
DP  - 1977 Mar 19
TA  - Canadian Medical Association Journal
PG  - 635--640
VI  - 116
IP  - 6
4099  - http://www.cmaj.ca/content/116/6/635.short
4100  - http://www.cmaj.ca/content/116/6/635.full
SO  - CMAJ1977 Mar 19; 116
AB  - In seven infants with DiGeorge syndrome the major clinical manifestation was cardiac failure in the 1st week of life. All had severe congenital heart disease: five had interruption of the aortic arch and associated lesions, one had a ventricular septal defect and a cervical aorta, and one had truncus arteriosus. All but one died by 2 weeks of age. Necropsy data lent support to the hypothesis of a relation between the cardiovascular anomalies and defective development of structures derived from the third and fourth pharyngeal pouches.