RT Journal Article SR Electronic T1 Drug management of pain in cancer patients JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 121 OP 134 VO 132 IS 2 A1 Tuttle, C. B. YR 1985 UL http://www.cmaj.ca/content/132/2/121.abstract AB Chronic severe cancer pain is often not well controlled because both patient and physician have a poor understanding of the nature of the pain and of the actions of various potent analgesics. Physicians often fail to tailor analgesic dosages to the needs of the individual and unnecessarily limit the dosage because they have an ill founded fear that the patient will become addicted. The basis of rational management of cancer pain with drugs is an appropriate analgesic given regularly in doses adequate to suppress pain continuously. This review compares the potent analgesics and identifies and discusses those that have a role in treating chronic cancer pain. It emphasizes the value of morphine sulfate and gives information on starting and individualizing dosages and managing side effects.