RT Journal Article
SR Electronic
T1 Current medical management of duodenal ulcer disease
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 1192
OP 1195
VO 117
IS 10
A1 Badley, B. W.
YR 1977
UL http://www.cmaj.ca/content/117/10/1192.abstract
AB Each of three agents used in the treatment of duodenal ulcer--magnesium--aluminum antacids in high doses, cimetidine and carbenoxolone sodium--appears to enhance the rate at which ulcers heal, although their ability to control symptoms has been less clearly demonstrated. Since a large proportion of ulcers heal either without treatment or when the patient is given a placebo, a rational management plan should emphasize the removal of known irritants and the provision of symptomatic relief while spontaneous healing is allowed to occur. Lack of response to such a regimen warrants more specific investigation and therapy. On the basis of current evidence, cimetidine appears to be the preferred therapeutic agent.