PT  - JOURNAL ARTICLE
AU  - Wright, V. C.
AU  - Lanning, N. M.
AU  - Natale, R.
TI  - Use of a topical antibiotic spray in vaginal surgery
DP  - 1978 Jun 10
TA  - Canadian Medical Association Journal
PG  - 1395--1398
VI  - 118
IP  - 11
4099  - http://www.cmaj.ca/content/118/11/1395.short
4100  - http://www.cmaj.ca/content/118/11/1395.full
SO  - CMAJ1978 Jun 10; 118
AB  - During vaginal hysterectomy with or without colporrhaphy a topical aerosol spray containing neomycin sulfate, polymyxin B sulfate and zinc bacitracin was used in 50 patients to decrease the change of postoperative pelvic infection; a placebo spray was used in another 50 patients. All patients were treated preoperatively with povidone iodine and postoperatively with nitrofurantoin and an antibacterial irrigating solution for the bladder if catheter drainage was necessary. The frequency of postoperative pelvic infection was 16% in the group sprayed with the antibiotic combination and 34% in the group sprayed with the placebo, a significant difference (P less than 0.05).