PT - JOURNAL ARTICLE AU - Dragatakis, L. N. AU - Klassen, J. AU - Huttner, I. AU - Fraser, D. G. AU - Poirier, N. L. AU - Klassen, G. A. TI - Autoimmune myocarditis: a clinical entity DP - 1979 Feb 03 TA - Canadian Medical Association Journal PG - 317--321 VI - 120 IP - 3 4099 - http://www.cmaj.ca/content/120/3/317.short 4100 - http://www.cmaj.ca/content/120/3/317.full SO - CMAJ1979 Feb 03; 120 AB - In a case of myocarditis electron microscopic and immunoflourescent studies of a transmural myocardial biopsy specimen indicated an autoimmune process. Extensive inflammatory cell infiltration, immunoglobulin and complement deposition along the sarcolemma and in the interstitium, and capillary endothelial injury were found. After a short course of immunosuppressive therapy the inflammatory process was replaced by collagenous scarring and lymphocytic depletion; the blood vessels were then normal. Earlier therapy in such cases may be lifesaving.