PT  - JOURNAL ARTICLE
AU  - Korula, J.
AU  - Malatjalian, D. A.
AU  - Badley, B. W.
TI  - Acute fatty liver of pregnancy
DP  - 1982 Oct 01
TA  - Canadian Medical Association Journal
PG  - 575--578
VI  - 127
IP  - 7
4099  - http://www.cmaj.ca/content/127/7/575.short
4100  - http://www.cmaj.ca/content/127/7/575.full
SO  - CMAJ1982 Oct 01; 127
AB  - Acute fatty liver of pregnancy (AFLP) is rare and is peculiar to the latter half of pregnancy. Despite the high rates of death among affected mothers and their fetuses, early recognition of the disease and immediate delivery of the infant may improve the chances of survival. This paper describes a case of AFLP, characterized by a rapid decrease in the size of the liver, a greatly prolonged prothrombin time and minimal increases in the serum transaminase levels, in which an immediate cesarean section followed by vigorous supportive care led to survival of both mother and infant. It is clear that guidelines on treatment are necessary if the management of such cases is to be successful.