RT Journal Article
SR Electronic
T1 Acute fatty liver of pregnancy
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 575
OP 578
VO 127
IS 7
A1 Korula, J.
A1 Malatjalian, D. A.
A1 Badley, B. W.
YR 1982
UL http://www.cmaj.ca/content/127/7/575.abstract
AB Acute fatty liver of pregnancy (AFLP) is rare and is peculiar to the latter half of pregnancy. Despite the high rates of death among affected mothers and their fetuses, early recognition of the disease and immediate delivery of the infant may improve the chances of survival. This paper describes a case of AFLP, characterized by a rapid decrease in the size of the liver, a greatly prolonged prothrombin time and minimal increases in the serum transaminase levels, in which an immediate cesarean section followed by vigorous supportive care led to survival of both mother and infant. It is clear that guidelines on treatment are necessary if the management of such cases is to be successful.