PT  - JOURNAL ARTICLE
AU  - Jackson, S. M.
AU  - Olivotto, I.
AU  - McLoughlin, M. G.
AU  - Coy, P.
TI  - Radiation therapy for seminoma of the testis: results in British Columbia
DP  - 1980 Sep 20
TA  - Canadian Medical Association Journal
PG  - 507--512
VI  - 123
IP  - 6
4099  - http://www.cmaj.ca/content/123/6/507.short
4100  - http://www.cmaj.ca/content/123/6/507.full
SO  - CMAJ1980 Sep 20; 123
AB  - Between 1942 and 1978 radiation therapy was given to 362 patients with seminoma of the testis, 40 (11%) of whom had a history of maldescent of either testis. The disease was classified retrospectively according to the extent of the primary tumor, the involvement of the regional lymph nodes and the presence of distant metastases (the TNM system), and the results of treatment were analysed according to the classifications. Among the 275 patients referred for treatment at least 5 years before this analysis the 5-year survival rates were 87% overall, 96% for those with a T1 or T2 (relatively localized) tumour but no evidence of nodal involvement or distant metastases and 62% for the 24 with palpable or distant metastases at the time of clinical presentation. Of the 28 patients in whom the disease recurred 15 were successfully treated. A second primary testicular tumour developed in the contralateral testis of eight patients. The incidence of other cancers was not increased over the expected rate in the general male population of the same age.