RT Journal Article SR Electronic T1 Acute nonlymphocytic leukemia following bladder instillations with thiotepa JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 578 OP 579 VO 129 IS 6 A1 Easton, D. J. A1 Poon, M. A. YR 1983 UL http://www.cmaj.ca/content/129/6/578.abstract AB A case of therapy-related leukemia is described. Other cases of acute nonlymphocytic leukemia have been associated with the intramuscular administration of thiotepa (an alkylating agent), but this patient received only intravesical instillations of the drug. The interval between the start of chemotherapy and the onset of leukemia was 56 months.