RT Journal Article
SR Electronic
T1 Vasodilators
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 424
OP 428
VO 129
IS 5
A1 Zsoter, T. T.
YR 1983
UL http://www.cmaj.ca/content/129/5/424.abstract
AB This article reviews the types, mechanisms of action and therapeutic applications of currently used vasodilators. Vasodilators have little value if there is vascular obstruction but are effective in the treatment of systemic hypertension and of myocardial ischemia and heart failure. Since the various groups of vasodilators have widely different actions on the coronary arteries, the peripheral arterial circulation and venous tone, an understanding of the specific modes of action and of the systemic effects of these drugs is essential if they are to be used appropriately and their side effects minimized.