PT - JOURNAL ARTICLE AU - Goldbloom, D. S. AU - Kennedy, S. H. AU - Kaplan, A. S. AU - Woodside, D. B. TI - Anorexia nervosa and bulimia nervosa DP - 1989 May 15 TA - Canadian Medical Association Journal PG - 1149--1154 VI - 140 IP - 10 4099 - http://www.cmaj.ca/content/140/10/1149.short 4100 - http://www.cmaj.ca/content/140/10/1149.full SO - CMAJ1989 May 15; 140 AB - No definitive therapy exists for anorexia nervosa (AN) or bulimia nervosa (BN). Nevertheless, biologic and psychologic research into these disorders has increased over the last decade. We examine the various drugs available for treatment. Advances in pharmacotherapy for AN have been modest and have reflected efforts either to stimulate hunger and weight gain or to control complications of the starvation process. Food remains the "drug" of choice. Antidepressants have been found to be beneficial in the treatment of BN. The meaning of this in the context of a relation between BN and mood disorders remains unclear, since coexistent depression does not predict a positive response to these drugs. Pharmacotherapy represents a single but important dimension of the management of patients with eating disorders. The optimal integration of drug therapy and psychotherapy and the identification of predictors of a positive response to drugs have yet to be addressed by clinical research.