PT  - JOURNAL ARTICLE
AU  - Thompson, W. G.
TI  - Nonulcer dyspepsia
DP  - 1984 Mar 01
TA  - Canadian Medical Association Journal
PG  - 565--569
VI  - 130
IP  - 5
4099  - http://www.cmaj.ca/content/130/5/565.short
4100  - http://www.cmaj.ca/content/130/5/565.full
SO  - CMAJ1984 Mar 01; 130
AB  - One third to one half of cases of dyspepsia remain unexplained. The cause of nonulcer dyspepsia is unknown, but aerophagia, esophageal dysfunction, pyloroduodenal dysmotility and the irritable bowel syndrome may be important factors in some patients. The symptoms are often affected by diet and emotion. History-taking and endoscopy are the most discriminating diagnostic tests. Unexplained dyspepsia tends to be a lifelong disease with few, if any, sequelae. Nevertheless, reassurance and treatment with a placebo, such as an antacid or simethicone, provide effective and safe relief for many patients.