PT  - JOURNAL ARTICLE
AU  - Lim, Sue
AU  - Katz, Kevin
AU  - Krajden, Sigmund
AU  - Fuksa, Milan
AU  - Keystone, Jay S.
AU  - Kain, Kevin C.
TI  - Complicated and fatal <em>Strongyloides</em> infection in Canadians: risk factors, diagnosis and management
AID  - 10.1503/cmaj.1031698
DP  - 2004 Aug 31
TA  - Canadian Medical Association Journal
PG  - 479--484
VI  - 171
IP  - 5
4099  - http://www.cmaj.ca/content/171/5/479.short
4100  - http://www.cmaj.ca/content/171/5/479.full
SO  - CMAJ2004 Aug 31; 171
AB  - STRONGYLOIDIASIS, WHICH IS CAUSED by the nematode Strongyloides stercoralis, is a common and persistent infection, particularly in developing countries. In the setting of compromised cellular immunity, it can result in fulminant dissemination with case-fatality rates of over 70%. The majority of new Canadian immigrants come from countries where Strongyloides is highly endemic; therefore, the burden of Strongyloides may be underappreciated in Canada. Because early diagnosis and therapy can have a marked impact on disease outcome, screening for this infection should be considered mandatory for patients who have a history of travel or residence in a disease-endemic area and risk factors for disseminated disease (e.g., corticosteroid use and human T-lymphotropic virus type I infection).