RT Journal Article SR Electronic T1 Photoplethysmography using a smartphone application for assessment of ulnar artery patency: a randomized clinical trial JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP E380 OP E388 DO 10.1503/cmaj.170432 VO 190 IS 13 A1 Di Santo, Pietro A1 Harnett, David T. A1 Simard, Trevor A1 Ramirez, F. Daniel A1 Pourdjabbar, Ali A1 Yousef, Altayyeb A1 Moreland, Robert A1 Bernick, Jordan A1 Wells, George A1 Dick, Alexander A1 Le May, Michel A1 Labinaz, Marino A1 So, Derek A1 Motazedian, Pouya A1 Jung, Richard G. A1 Chandrasekhar, Jaya A1 Mehran, Roxana A1 Chong, Aun-Yeong A1 Hibbert, Benjamin YR 2018 UL http://www.cmaj.ca/content/190/13/E380.abstract AB BACKGROUND: Radial artery access is commonly performed for coronary angiography and invasive hemodynamic monitoring. Despite limitations in diagnostic accuracy, the modified Allen test (manual occlusion of radial and ulnar arteries followed by release of the latter and assessment of palmar blush) is used routinely to evaluate the collateral circulation to the hand and, therefore, to determine patient eligibility for radial artery access. We sought to evaluate whether a smartphone application may provide a superior alternative to the modified Allen test.METHODS: We compared the modified Allen test with a smartphone heart rate–monitoring application (photoplethysmography readings detected using a smartphone camera lens placed on the patient’s index finger) in patients undergoing a planned cardiac catheterization. Test order was randomly assigned in a 1:1 fashion. All patients then underwent conventional plethysmography of the index finger, followed by Doppler ultrasonography of the radial and ulnar arteries (the diagnostic standard). The primary outcome was diagnostic accuracy of the heart rate–monitoring application.RESULTS: Among 438 patients who were included in the study, we found that the heart rate–monitoring application had a superior diagnostic accuracy compared with the modified Allen test (91.8% v. 81.7%, p = 0.002), attributable to its greater specificity (93.0% v. 82.8%, p = 0.001). We also found that this application had greater diagnostic accuracy for assessment of radial or ulnar artery patency in the ipsilateral and contralateral wrist (94.0% v. 84.0%, p < 0.001).INTERPRETATION: A smartphone application used at the bedside was diagnostically superior to traditional physical examination for confirming ulnar patency before radial artery access. This study highlights the potential for smartphone-based diagnostics to aid in clinical decision-making at the patient’s bedside. Trial registration: Clinicaltrials.gov, no. NCT02519491.See related article at www.cmaj.ca/lookup/doi/10.1503/cmaj.180269