RT Journal Article SR Electronic T1 Hypoglycemia as a complication of removal of a pheochromocytoma JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 363 OP 364 VO 116 IS 4 A1 Allen, C. T. A1 Imrie, D. YR 1977 UL http://www.cmaj.ca/content/116/4/363.abstract AB In a patient with a solitary pheochromocytoma severe hypoglycemia developed following excision of the tumour. The possible causative mechanism was thought to be a reactive relative increase in insulin production secondary to increased endogenous production of glucose, induced by the large amounts of epinephrine produced by the tumour. Alternatively, epinephrine withdrawal following removal of the tumour under phentolamine infusion may have induced increased insulin production and hence potentiated the development of hypoglycemia. Careful monitoring of the blood glucose concentration during and after the operation is recommended to obviate this potentially fatal complication.