Table 2:

Summary of participant perspectives on factors related to SARS-CoV-2 vaccinations for children

ThemeDissuading factorsPersuading factors
Newness of SARS-CoV-2 vaccines and supporting evidence
  • Uncertainty about vaccine risks and adverse effects, given their newness

  • New mRNA technology and limited understanding thereof

  • Lack of clear evidence of benefit or need of SARS-CoV-2 vaccine for children

  • Perception that SARS-CoV-2 vaccine is different, and therefore less trustworthy, than other (routine) childhood vaccines

  • Perception that risk of vaccine outweighs risk of COVID-19 (based on either sparse evidence regarding long-term adverse effects or individual stories of adverse effects)

  • Reduced opportunities for in-person discussions with health care providers because of the shift to virtual care

  • Trust in evidence supporting vaccines, despite their newness

  • Perception that risk of COVID-19 outweighs potential risk of vaccine (based on appraisal of evidence or experience witnessing individuals contracting SARS-CoV-2)

  • Consultation with trusted sources (e.g., health care providers, colleagues)

Politicization of SARS-CoV-2 guidance
  • Perception that guidance for SARS-CoV-2 vaccination is politically or financially motivated

  • Distrust of politicians who may have biases or agendas

  • Distrust of media who are seen as having taken sides or fear mongering

  • Dissatisfaction with government involvement in health care decisions, including public health measures for COVID-19 (e.g., masking and social distancing requirements).

  • Widespread messaging (from politicians, news sources, social media, etc.) keeping vaccination top of mind

Social pressure surrounding SARS-CoV-2 vaccinations
  • Pressure from family members to not get vaccinated

  • Inability to ask questions or voice concerns for fear of being labelled “anti-vax”

  • Pressure from family members to get vaccinated

  • Fear of stigma or exclusion if unvaccinated (e.g., kids being excluded from sports teams, being ostracized at school)

The weighing of individual v. collective benefit
  • Unease about putting foreign substances into children who are still developing (most concerning for younger children)

  • Concern about potential vaccine adverse effects because of perceived parental responsibility or child’s specific medical condition

  • Lack of perceived need for their own child because of previous infection, adherence to measures such as masking or perceived health of child

  • Lack of convincing evidence of the public health benefits of vaccinations for children

  • Perception that children should not be responsible for the health of others

  • Individual protection against SARS-CoV-2

  • Public health benefits (e.g., reducing spread, herd immunity, protecting others)

  • Desire for return to normalcy (e.g., kids socializing again, no longer wearing masks, returning to in-person classrooms)

  • Allowing children to make choice for themselves