Table 2:

Testing for chlamydia and gonorrhea

Site	Approach for asymptomatic patients or screening	Approach for symptomatic patients
Penile urethra	First-void urine for NAAT for chlamydia and gonorrhea	Urethral swab for gonorrhea culture and sensitivity testing, and first-void urine for NAAT for chlamydia and gonorrhea
Cervix or vagina^*	Vaginal swab (preferred), cervical swab or first-void urine for NAAT for chlamydia and gonorrhea	Cervical swab for gonorrhea culture and sensitivity testing, and for NAAT for chlamydia and gonorrhea, or Vaginal swab for gonorrhea culture and sensitivity testing, and for NAAT for chlamydia and gonorrhea, or First-void urine for NAAT for chlamydia and gonorrhea
Throat	Throat swab for NAAT for chlamydia and gonorrhea	Throat swab for gonorrhea culture and sensitivity testing, and for NAAT for chlamydia and gonorrhea
Rectum	Rectal swab for NAAT for chlamydia and gonorrhea	Rectal swab for gonorrhea culture and sensitivity testing, and for NAAT for chlamydia and gonorrhea

Note: NAAT = nucleic acid amplification test.
↵* For patients with a neovagina, a first-void urine is the preferred screening test. In symptomatic patients, efforts should be made to conduct gonorrhea culture and sensitivity testing, as well as NAAT for chlamydia and gonorrhea. When culture and sensitivity testing is not possible, either a cervical or vaginal swab for NAAT or a first-void urine is appropriate.