Table 4:

Adjusted* effect of interventions by outcome

VariableAntimicrobial; OR (95% CI)
First-lineNitrofurantoinQuinoloneTrimethoprimCo-amoxyclav
ControlReferenceReferenceReferenceReferenceReference
Arm A2.7 (1.8 to 4.1)4.5 (2.7 to 7.3)0.6 (0.3 to 1.00)0.3 (0.1 to 0.6)0.4 (0.3 to 0.7)
Arm B2.0 (1.3 to 3.0)3.5 (1.9 to 6.3)0.7 (0.3 to 1.4)0.2 (0.1 to 0.3)0.3 (0.2 to 0.6)
Age, per yr1.0 (0.99 to 1.0)1.0 (1.0 to 1.0)1.0 (1.0 to 1.0)1.0 (0.98 to 1.0)0.99 (0.99 to 1.0)
Sex, male0.5 (0.4 to 0.7)0.6 (0.4 to 0.8)2.4 (1.5 to 3.9)0.7 (0.4 to 1.2)0.9 (0.5 to 1.7)
Medical card1.1 (0.9 to 1.3)1.0 (0.8 to 1.3)0.7 (0.4 to 0.98)1.2 (0.9 to 1.5)1.1 (0.8 to 1.5)
ICC0.0480.0450.0350.0310.005
  • Note: CI = confidence interval, ICC = intraclass correlation (measure of resemblance among practices), OR = odds ratio.

  • * ORs were adjusted for age, sex, medical card status and number of antimicrobial prescriptions per 100 practice consultations.