Table 4:

Prognostic factors in Parkinson disease (57)

Predictors of a more benign coursePredictors of a more rapid course

  • Early onset (24)

  • Tremor-predominant

  • Female sex (118)

  • Late onset (24)

  • Male sex (118)

  • Postural instability (predominant gait difficulty)

  • Rigidity or bradykinesia as first symptom

  • Dementia

  • Poor response to levodopa

  • Associated comorbidities (e.g., stroke)