Incidence and subhazard ratio of acute kidney injury, chronic kidney disease and end-stage renal disease in propensity score–matched cohorts, using competing-risks regression models
| Outcome | Competing-risks regression models | |
|---|---|---|
| Critical illness | ||
| No n = 14 218 (95% CI) | Yes n = 14 218 (95% CI) | |
| Acute kidney injury | ||
| Crude SHR | 1 (Reference) | 1.73 (1.16–2.58) |
| Adjusted SHR* | 1 (Reference) | 1.85 (1.23–2.79) |
| Chronic kidney disease | ||
| Crude SHR | 1 (Reference) | 1.72 (1.50–1.97) |
| Adjusted SHR* | 1 (Reference) | 1.73 (1.51–1.98) |
| End-stage renal disease | ||
| Crude SHR | 1 (Reference) | 2.92 (2.13–4.00) |
| Adjusted SHR* | 1 (Reference) | 2.91 (2.11–4.00) |
Note: CHF = congestive heart failure, CI = confidence interval, COPD = chronic obstructive pulmonary disease, SHR = subhazard ratio.
Covariables found significantly associated with acute kidney injury, chronic kidney disease and end-stage renal disease in the univariable competing-risks regression model were further examined by the multivariable competing-risks regression model.
Adjusted SHR for acute kidney injury by propensity score matching was calculated by Cox proportional hazard regression and adjusted for age, sex and comorbidities of diabetes, hypertension, CHF and admission to intensive care unit.
Adjusted SHR for chronic kidney disease by propensity score matching was calculated by Cox proportional hazard regression and adjusted for age, sex and comorbidities of diabetes, hypertension, hyperlipidemia, CHF and COPD.
Adjusted SHR for end-stage renal disease by propensity score matching was calculated by Cox proportional hazard regression and adjusted for age, sex, Charlson Comorbidity Index score and comorbidities of diabetes, hypertension, hyperlipidemia, CHF and COPD.