Crude and adjusted odds ratios for higher abundance (≥ median) of key infant gut microbiota at 3–4 months with frequent household use of disinfectants
| Ref: Lower use of disinfectants | Crude model (n = 757) OR (95% CI) | Adjusted model* (n = 699) AOR (95% CI) |
|---|---|---|
| Bifidobacteriaceae (below v. above median) | 0.89 (0.67 to 1.19) | 1.00 (0.73 to 1.39) |
| Coriobacteriaceae (below v. above median) | 1.40 (1.05 to 1.86) | 1.47 (1.05 to 2.06) |
| Lachnospiraceae (below v. above median) | 1.67 (1.26 to 2.23) | 1.34 (1.02 to 1.90) |
| Genus Ruminococcus (below v. above median) | 1.47 (1.11 to 1.96) | 1.55 (1.10 to 2.17) |
| Ruminococcaceae (below v. above median) | 1.42 (1.07 to 1.89) | 1.15 (0.80 to 1.64) |
| Genus Oscillospira (below v. above median) | 1.39 (1.05 to 1.85) | 1.04 (0.74 to 1.47) |
| Erysipelotrichaceae (below v. above median) | 1.25 (0.94 to 1.67) | 0.90 (0.61 to 1.22) |
| Genus Clostridium (below v. above median) | 0.74 (0.55 to 0.98) | 0.61 (0.43 to 0.86) |
| Genus Veillonella (below v. above median) | 0.88 (0.66 to 1.17) | 0.73 (0.52 to 1.02) |
| Enterobacteriaceae (below v. above median) | 0.81 (0.61 to 1.07) | 0.82 (0.58 to 1.15) |
| Pasteurellaceae (below v. above median)† | 0.65 (0.49 to 0.87) | 0.67 (0.48 to 0.95) |
| Genus Haemophilus (below v. above median)† | 0.68 (0.51 to 0.90) | 0.69 (0.49 to 0.98) |
Note: AOR = adjusted odds ratio, CI = confidence interval, OR = odds ratio.
↵* Adjusted for mode of delivery, breastfeeding status, direct and indirect exposure to antibiotics, and household detergent in first 3 months, and fecal sampling age.
↵† Adjusted for mode of delivery, breastfeeding status, direct and indirect exposure to antibiotics, household smoking and household detergent in first 3 months, and fecal sampling age (n = 698).