Model parameters used in the transmission model*
Parameter | Age group, yr | Health status | Value | Details | Source |
---|---|---|---|---|---|
Latent period, d | All | All | 2.5 | Time from exposure to onset of infectiousness | References (18)– (20) |
Presymptomatic infectious period, d | All | All | 1 | Duration of infectiousness before symptom onset | References (18)– (20) |
Infectious period (mild to moderate), d | All | All | 6 | Symptomatic infectious period for mild-to- moderate cases (in absence of isolation) | References (18)– (20) |
Infectious period (severe), d | All | All | 6 | Symptomatic infectious period for infectiousness for severe cases; assumed equal to time to hospital admission | References (18)– (20) |
Basic reproduction number | All | All | 2.3 | Average number of secondary infections derived from a primary infection in a susceptible population | Reference (6) |
Time in quarantine, d | All | All | 14 | Duration of quarantine for exposed cases | Current policy |
Relative risk of transmission for cases in isolation | All | All | 0.1 | Isolated cases are assumed to have reduced transmission relative to unrecognized cases | Assumption |
Average length of stay in hospital for cases not requiring ICU care, d | All | All | 10 | Reference (21) | |
Average length of stay in hospital before ICU admission, d | All | All | 3 | For severe cases requiring ICU care | Reference (21) |
Average length of stay in ICU, d | All | All | 21 | For severe cases requiring ICU care | Reference (22) |
Average length of stay in hospital after ICU, d | All | All | 21 | For severe cases requiring ICU care | Reference (22) |
Probability of severe infection | Severe infections requiring hospital admission | Reference (21) | |||
< 15 | No comorbidities | 0.01 | |||
15–49 | No comorbidities | 0.03 | |||
50–69 | No comorbidities | 0.12 | |||
≥ 70 | No comorbidities | 0.35 | |||
< 15 | Comorbidities | 0.02 | |||
15–49 | Comorbidities | 0.06 | |||
50–69 | Comorbidities | 0.25 | |||
≥ 70 | Comorbidities | 0.76 | |||
Probability severe case requires admission to ICU | All | All | 0.26 | Reference (21) | |
Probability of death in cases admitted to ICU | Reference (22) | ||||
< 15 | No comorbidities | 0 | |||
15–49 | No comorbidities | 0.2 | |||
50–69 | No comorbidities | 0.36 | |||
≥ 70 | No comorbidities | 0.58 | |||
< 15 | Comorbidities | 0 | |||
15–49 | Comorbidities | 0.53 | |||
50–69 | Comorbidities | 0.9 | |||
≥ 70 | Comorbidities | 1 |
Note: ICU = intensive care unit.
↵* A full model description is provided in Appendix 1 (available at www.cmaj.ca/lookup/suppl/doi:10.1503/cmaj.200476/-/DC1). Age group and health status refer to the population groups to which the parameter value was applied.